Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 6HeBV | 6HeBV32 | U.S. | 1994 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 32 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | I15V, M36I, L63P, K70Q |
| >6HeBV32| 1 | codons 1-99 | clone 1 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLMTQIGCTLNF >6HeBV32| 2 | codons 1-99 | clone 2 PQITLWQRPVVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV32| 3 | codons 1-99 | clone 3 PQITLWQRPLVTIKVGGQLKEALLDTGADNTVLEEINLPGRWKPKLIGGIGGFVKVRQHD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV32| 4 | codons 1-99 | clone 4 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLSTQIGCTLNF >6HeBV32| 5 | codons 1-99 | clone 5 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV32| 6 | codons 1-99 | clone 6 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV32| 7 | codons 1-99 | clone 7 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCALNF >6HeBV32| 8 | codons 1-99 | clone 8 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV32| 9 | codons 1-99 | clone 9 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV32| 10 | codons 1-99 | clone 10 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV32| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |