Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1978 | UK1978 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI+ EFV | NA |
| 2 | NVP+ AZT+ 3TC | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, L63V, H69K, L89M |
| >UK1978| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | V35T, V60I, D121H, K122E, I135T, T139R, I142V, K173L, Q174K, D177E, I178L, V179I, I202V, Q207E, R211S | M41I |
| >UK1978| codons 1-232 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEIEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNERPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPELII YQYVDDLYVGSDLEIGQHRTKVEELREHLLSWGFTTPDKKHQKEPPFLWMGY |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |