<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
6HeBV 6HeBV20 U.S. 1994 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NRTI+IDV 20

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A   I15V, L63P, K70Q  
>6HeBV20| 1 | codons 1-99 | clone 1
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV20| 2 | codons 1-99 | clone 2
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLMTQIGCTLNF
>6HeBV20| 3 | codons 1-99 | clone 3
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGEIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV20| 4 | codons 1-99 | clone 4
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV20| 5 | codons 1-99 | clone 5
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV20| 6 | codons 1-99 | clone 6
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV20| 7 | codons 1-99 | clone 7
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV20| 9 | codons 1-99 | clone 9
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QIPMEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV20| 10 | codons 1-99 | clone 10
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV20| 11 | codons 1-99 | clone 11
PQITLWKRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV20| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005