Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 6HeBV | 6HeBV20 | U.S. | 1994 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 20 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | I15V, L63P, K70Q |
| >6HeBV20| 1 | codons 1-99 | clone 1 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV20| 2 | codons 1-99 | clone 2 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLMTQIGCTLNF >6HeBV20| 3 | codons 1-99 | clone 3 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGEIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV20| 4 | codons 1-99 | clone 4 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV20| 5 | codons 1-99 | clone 5 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV20| 6 | codons 1-99 | clone 6 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV20| 7 | codons 1-99 | clone 7 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV20| 9 | codons 1-99 | clone 9 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPMEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV20| 10 | codons 1-99 | clone 10 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV20| 11 | codons 1-99 | clone 11 PQITLWKRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV20| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |