<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
6HeBV 6HeBV16 U.S. 1993 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NRTI+IDV 16

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, V82A   I15V, M36I, L63P, K70Q  
>6HeBV16| 1 | codons 1-99 | clone 1
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEIILPGRWKPKLIGGVGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV16| 2 | codons 1-99 | clone 2
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV16| 3 | codons 1-99 | clone 3
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLWTQIGCTLNF
>6HeBV16| 4 | codons 1-99 | clone 4
PQITLWQRPLITIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV16| 6 | codons 1-99 | clone 6
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV16| 7 | codons 1-99 | clone 7
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV16| 8 | codons 1-99 | clone 8
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV16| 9 | codons 1-99 | clone 9
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGRTLNF
>6HeBV16| 10 | codons 1-99 | clone 10
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGVGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV16| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005