<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
6HeBV 6HeBV10 U.S. 1993 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 10

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, V82A   I15V, M36I, L63P, K70Q  
>6HeBV10| 19 | codons 1-99 | clone 19
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV10| 20 | codons 1-99 | clone 20
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV10| 21 | codons 1-99 | clone 21
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV10| 22 | codons 1-99 | clone 22
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV10| 23 | codons 1-99 | clone 23
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV10| 25 | codons 1-99 | clone 25
PQITLWQRPLATIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV10| 26 | codons 1-99 | clone 26
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIPIEIYGHQAIGTVLVGPTPANIIGRNLLTQISCTLNF
>6HeBV10| 27 | codons 1-99 | clone 27
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV10| 28 | codons 1-99 | clone 28
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLVGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV10| 29 | codons 1-99 | clone 29
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>6HeBV10| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD
QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005