Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 6HeBV | 6HeBV6 | U.S. | 1993 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 6 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, V82A | I15V, L63P, K70Q |
| >6HeBV6| 38 | codons 1-99 | clone 38 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV6| 39 | codons 1-99 | clone 39 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >6HeBV6| 40 | codons 1-99 | clone 40 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV6| 41 | codons 1-99 | clone 41 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >6HeBV6| 42 | codons 1-99 | clone 42 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV6| 43 | codons 1-99 | clone 43 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFI*VRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV6| 44 | codons 1-99 | clone 44 PQITPWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGMGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPVNIVGRDLLTQIGCTLNF >6HeBV6| 46 | codons 1-99 | clone 46 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPVNIVGRDLLTQIGCTLNF >6HeBV6| 47 | codons 1-99 | clone 47 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV6| 48 | codons 1-99 | clone 48 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >6HeBV6| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |