Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PW_UG477 | PW_UG477a | Uganda | 1997 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 34 |
| 2 | AZT+ DDI | 10 |
| 3 | AZT+ 3TC+ SQV | 24 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K20R, M36I, R41K, Q61E, H69K, V82VI, L89M, I93L |
| >PW_UG477a| codons 1-99 PQITLWQRPLVTIKIGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD EILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | V35T, E36EA, T39E, K122E, D123GS, I135IM, I142V, K173A, D177E, T200A, I202V, Q207E, V245Q, A272P, I274IV, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359A, T377Q, K390R, A400AT | K277V |
| >PW_UG477a| codons 1-400 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSMNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAKVEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGVKVVQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRRAA HTNDVKQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWET |
References
| Author | Title | Citation |
| Weidle, PJ | Resistance to antiretroviral therapy among patients in Uganda. | JAIDS, 2001 |