Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PW_UG474 | PW_UG474 | Uganda | 1998 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V75I | P4T, V35T, T39TA, K49R, I50V, V60I, D121Y, K122E, D123E, K126Q, I132L, I142V, Q174QK, D177E, Q207E, F214L, I244V, V245K, D250E, A272P, T286A, G335D, M357K, G359S, A360V, T377L, T386I, K388KR, K390R, A400T |
| >PW_UG474| codons 1-400 PISTIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISRVGPENPYNTPI FAIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEEFRQYTAFTLPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPVKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSV HTNDVKQLTEAVQKIALESIVIWGKIPRFRLPIQKETWET |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, M36I, R41K, L63X, I64V |
| >PW_UG474| codons 1-99 PQITLWQRPVVTVKIGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIXVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Weidle, PJ | Resistance to antiretroviral therapy among patients in Uganda. | JAIDS, 2001 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |