Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 5MuBV | 5MuBV29 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 29 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82T | K14R, R41K, I64V, I93L |
| >5MuBV29| 49 | codons 1-99 | clone 49 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQLGCTLNF >5MuBV29| 50 | codons 1-99 | clone 50 PQITLWQRPLVTMRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQLGCTLNF >5MuBV29| 51 | codons 1-99 | clone 51 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD QVLVEICGHKAIGTVVVGPTPANIIGRNLLTQIGCTLNF >5MuBV29| 52 | codons 1-99 | clone 52 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD QVLVEICGHKAIGTVVVGPTPVNIIGRNLLTQIGCTLNF >5MuBV29| 53 | codons 1-99 | clone 53 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF >5MuBV29| 54 | codons 1-99 | clone 54 PQITLWQPPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWTPKIIGGIGGFIKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRDLLTQLGCTLNF >5MuBV29| 55 | codons 1-99 | clone 55 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWTPKIIGGIGGFIKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF >5MuBV29| 56 | codons 1-99 | clone 56 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD QILIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF >5MuBV29| 57 | codons 1-99 | clone 57 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD QVLVEICGHNAIGTVVVGPTPVNIIGRNLLTQIGCTLNF >5MuBV29| 58 | codons 1-99 | clone 58 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKLIGGIGGFIRVRQYD QILIEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >5MuBV29| codons 1-99 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIKVRQYD QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |