<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
5MuBV 5MuBV29 U.S. 1994 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 29

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82T   K14R, R41K, I64V, I93L  
>5MuBV29| 49 | codons 1-99 | clone 49
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQLGCTLNF
>5MuBV29| 50 | codons 1-99 | clone 50
PQITLWQRPLVTMRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD
QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQLGCTLNF
>5MuBV29| 51 | codons 1-99 | clone 51
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD
QVLVEICGHKAIGTVVVGPTPANIIGRNLLTQIGCTLNF
>5MuBV29| 52 | codons 1-99 | clone 52
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD
QVLVEICGHKAIGTVVVGPTPVNIIGRNLLTQIGCTLNF
>5MuBV29| 53 | codons 1-99 | clone 53
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIKVRQYD
QIPIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>5MuBV29| 54 | codons 1-99 | clone 54
PQITLWQPPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWTPKIIGGIGGFIKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRDLLTQLGCTLNF
>5MuBV29| 55 | codons 1-99 | clone 55
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWTPKIIGGIGGFIKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF
>5MuBV29| 56 | codons 1-99 | clone 56
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD
QILIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>5MuBV29| 57 | codons 1-99 | clone 57
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIRVRQYD
QVLVEICGHNAIGTVVVGPTPVNIIGRNLLTQIGCTLNF
>5MuBV29| 58 | codons 1-99 | clone 58
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKLIGGIGGFIRVRQYD
QILIEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>5MuBV29| codons 1-99
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIKVRQYD
QILVEICGHKAIGTVLVGPTPTNIIGRNLLTQLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005