Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KER2010 | KER2010 | Kenya | 2000 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L19I, K20R, M36I, R41K, I62V, L63I, H69K, A71T, L89I, I93L |
| >KER2010| codons 1-99 PQITLWQRPLVTVKIGGQIREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QVIIEICGKKTIGTVLVGPTPVNIIGRNILTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39E, S48E, D123N, I135R, K173A, Q174K, D177E, T200A, Q207E, V245Q, E248D, A272P, K275R, K277R, Q278H, E291D, V292I, I293V, E308A, Q334H, G335D, R356K, G359T, K385R, K390R, A400T, E404D, E432D, V435A, L452V, L469I, T470S, D471E, H483Q, L491S, S519N, K527R, A534S, A554S |
| >KER2010| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKIEKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKNFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIRVRHLCKLLRGTKALTDIVPLTEEAE LELAENRAILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIATESIVIWGRTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGAETFYVDGAANRETKVGKAGYVTDRGRQKVVSISETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIRKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, V31I, M50T, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K211R, T218I, K219Q, L234I, R269K, D278A | S283G |
| >KER2010| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIQIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Dowling, WE | Forty-one near full-length HIV-1 sequences from Kenya reveal an epidemic of subtype A and A-containing recombinants. | AIDS, 2002 |