Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KNH1043 | KNH1043 | Kenya | 1999 | HIV1 | CRF06_cpx | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V11I | I13V, K14R, L19I, K20I, M36I, R41K, C67E, H69K, V82I, L89M |
| >KNH1043| codons 1-99 PQITLWQRPLITVRIGGQIIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39M, V60I, K122E, D123G, K173T, Q174R, I178M, V189I, T200A, Q207E, R211K, K223R, V245Q, E248D, K275Q, V276T, V292I, I293V, G335D, F346Y, R356K, M357R, R358G, G359S, A376C, T386I, Q394R, A400I, E404D, E413D, Q428R, K431T, V435P, F440Y, V458I, R463K, V467A, S468N, D471E, T477A, H483Q, L491S, K512R, S519N, A534S, A554S |
| >KNH1043| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPDMVI YQYMDDLYIGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQREPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIQTKQLCKLLRGTKALTEIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPYKNLKTGKYAKRGSA HTNDVKQLTEAVQKICTESIVIWGKIPKFKLPIRKETWEIWWTDYWQATWIPDWEFVNTP PLVKLWYRLETEPIPGAETYYVDGAANRETKLGKAGYITDRGKQKVANLTETTNQKAELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| L68V | K14R, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, T206S | S283G |
| >KNH1043| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHVEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Dowling, WE | Forty-one near full-length HIV-1 sequences from Kenya reveal an epidemic of subtype A and A-containing recombinants. | AIDS, 2002 |