<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
KNH1097 KNH1097 Kenya 1999 HIV1 A PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, E35D, M36I, P39A, R41K, K45R, R57K, L63P, H69K, L89M  
>KNH1097| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLAGKWKPRMIGGIGGFIKVKQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V8I, K11T, P14A, K20R, V35T, T39R, D123S, I135T, K173S, D177E, V179I, I202V, Q207A, R211S, F214L, V245Q, E248N, T286A, E291D, V292I, I293V, P294T, E312N, Q334H, G335D, M357K, R358K, G359S, A371V, I375V, T386I, A400T, T403I, E404D, E432D, V435P, V467A, S468P, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S, V559I  
>KNH1097| codons 1-560
PISPIETIPVTLKAGMDGPRVKQWPLTEEKIKALTEICREMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKSFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIII
YQYMDDLYVGSDLEIGQHRTKVEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKNPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYARKKSA
HTNDVKQLTEVVQKVATESIVIWGKIPKFKLPIQKETWETWWIDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIPGAETFYVDGAANRETKLGKAGYVTDRGRQKVAPLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIEKDKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKIL

References
Author Title Citation
Dowling, WE Forty-one near full-length HIV-1 sequences from Kenya reveal an epidemic of subtype A and A-containing recombinants. AIDS, 2002