Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MSA4069 | MSA4069 | Kenya | 2000 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, K14R, G16E, E35D, M36I, N37D, R41K, H69K, L89M |
| >MSA4069| codons 1-99 PQITLWQRPVVTVRIEGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39M, V60I, D123S, I135T, Q145C, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, R211S, F214L, D250E, T286A, E291D, V292I, I293V, E312D, G335D, M357K, G359S, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D, T450N, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524E, E529D, A534S, A554N |
| >MSA4069| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKSFRKYTAFTIPSTNNETPGIRYCYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYMDDLYVGSDLEIGQHRAKVEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVKQLTEVVQKVVMESIVIWGKTPKFKLPIQKETWETWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAANRENKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEELIKKDKVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, V32I, S39C, M50I, I72V, L101I, T112V, I113V, T124A, T125A, G134N, K136Q, V201I, D270E | S283G |
| >MSA4069| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASDFNLPPVIAKEIVACCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVVHTDNGSN FTSAAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIREYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Dowling, WE | Forty-one near full-length HIV-1 sequences from Kenya reveal an epidemic of subtype A and A-containing recombinants. | AIDS, 2002 |