<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
RES050 RES050 South Africa 2011 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 214

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, T215F V75T V106M V179D, F227L V35T, E36A, T39D, S48T, E53D, V60I, K103R, L109I, K122E, D123N, I132L, K173I, Q174K, T200A, Q207E, R211K, F214L, K223R, A272P, K277R, T286A, E291D, V292I, I293V  
>RES050| codons 1-299
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDELEKEGKITKIGPDNPYNTPI
FAIKKKDSTKWRKVTDFRELNKRTQDFWEVQLGIPHPAGLKKRKSMTVIDVGDAYFSVPL
DENFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIDI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLFTPDKKHQREPPLLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, M36I, R41K, D60E, Q61E, H69K, L89M, I93L  
>RES050| codons 1-99
PQITLWQRPLVSIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
EILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Manasa, J High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa. PLoS ONE, 2013