<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NRTI|NNRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y K219N     V35I, T39E, E44D, V118I, I135T, I142V, S162C, E169D, V179I, T200A, I202V, R211K, V245E, T286A, V292I, E297Q, V317A, I329L, V365I, T386A, K395R  
>2536365721| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICEELEKDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILDPFRKQNPDIII
YQYMDDLYVGSDLEIGQHRAKVEELRQHLWKWGFYTPDNKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEIIPLTQEAE
LELAENREILKEPVHGAYYDPSKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDIKQLTEAVQKIATESIVIWGKAPKFKLPIQRETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A L10F, L24I, Q58E I15V, K20M, E35D, M36V, R57K, I62V, L63P, I64V, T74K  
>2536365721| codons 1-99
PQITLWQRPFVTIKVGGQLMEALIDTGADDTVLEDVNLPGRWKPKLIGGIGGFVKVKEYD
QVPVEICGHKAIGKVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Margot, NA Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF. AIDS, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005