Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7DiBV | 7DiBV0 | U.S. | 1993 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33I | K14R, I62V, L63P, A71T, I93L |
| >7DiBV0| 10 | codons 1-99 | clone 10 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 13 | codons 1-99 | clone 13 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 14 | codons 1-99 | clone 14 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKIIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 15 | codons 1-99 | clone 15 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 16 | codons 1-99 | clone 16 PQITL*QRPLVTIRIGGQLKEALLGTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 29 | codons 1-99 | clone 29 PQITLWQRPLVTIRIGGQLKEALLHTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIQICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 31 | codons 1-99 | clone 31 PQITLWQRPLVTIKMGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 33 | codons 1-99 | clone 33 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 34 | codons 1-99 | clone 34 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 35 | codons 1-99 | clone 35 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| 40 | codons 1-99 | clone 40 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNSPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV0| codons 1-99 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Wu, TD | Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. | J Virol, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |