<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
7DiBV 7DiBV0 U.S. 1993 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33I K14R, I62V, L63P, A71T, I93L  
>7DiBV0| 10 | codons 1-99 | clone 10
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 13 | codons 1-99 | clone 13
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 14 | codons 1-99 | clone 14
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKIIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 15 | codons 1-99 | clone 15
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 16 | codons 1-99 | clone 16
PQITL*QRPLVTIRIGGQLKEALLGTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 29 | codons 1-99 | clone 29
PQITLWQRPLVTIRIGGQLKEALLHTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIQICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 31 | codons 1-99 | clone 31
PQITLWQRPLVTIKMGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 33 | codons 1-99 | clone 33
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 34 | codons 1-99 | clone 34
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 35 | codons 1-99 | clone 35
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVVEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| 40 | codons 1-99 | clone 40
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNSPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV0| codons 1-99
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005