<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NRTI|NNRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32VI, M46MI, V82VA L10LHFY, K43KT T12TA, R41K, I62IV, L63P, T74A, V77VI, I93L  
>2042365081| codons 1-99
PQITLWQRPHVAIKIGGQLKEALLDTGADDTILEEMNLPGKWTPKIIGGIGGFIKVRQYD
QVPIEICGHKAIGAVLIGPTPANIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, T215F K219Q K103KN, Y181YC   P4PS, I135T, I178IV, T200TA, I202V, R211TK, V245AT, I293V, V317A, Q334N, I375V, T377TA, T386I  
>2042365081| codons 1-400
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDVVI
CQYMDDLYVGSDLEIGQHRAKVEELRQHLLTWGFFTPDQKHQKEPPFLWMGYELHPDKWT
VQPIALPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGNGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKVAAESIVIWGKIPKFKLPIQKETWEA

References
Author Title Citation
Margot, NA Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF. AIDS, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005