Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MM-562136822 | 5621368221 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI|NNRTI|PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M | A62V, V75I, F77L, F116Y | K103N | V108I | E6K, V118I, D123E, Q174H, I202V, R211K, K281R, T286A, P294T, E297K, R356K, T369V, K385R |
| >5621368221| codons 1-400 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKDSTKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYYSIPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKHNPDIVI YQYMDDLYVGSDLEIGQHRTKVEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTEVITLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRGA HTNDVKQLVEAVQKIATESIVIWGRTPKFKLPIQKETWEA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82A | L10I, K14R, N37D, K45R, L63P, K70R, V77I, I93L |
| >5621368221| codons 1-99 PQITLWQRPIVTIRIGGQLKEALLDTGADDTVLEEMDLPGRWKPRMIVGIGGFVKVRQYD QIPIEICGHRAIGTVLIGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Margot, NA | Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF. | AIDS, 2002 |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |