<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NRTI|NNRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88S   L10I, I13V, K20T, E35D, M36I, N37D, D60E, Q61D, I62V, L63P, C67Y, I72T  
>5535366291| codons 1-99
PQITLWQRPIVTVKIGGQLTEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVRQYE
DVPIEIYGHKATGTVLVGPTPVNIIGRSLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T215F   K103N   V8VI, K20R, V35VE, T39TA, E44ED, V60I, K64KR, I135IL, R211K, K275R, V292I, I293V, D324E, Q334H, P345PL, R358RK, A360T, K366R, T369V, E370ED, A371V, V372I, I375V, A376S, I382IL  
>5535366291| codons 1-400
PISPIETIPVKLKPGMDGPRVKQWPLTEEKIKALEEICAELEKDGKISKIGPENPYNTPI
FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIRVKQLCKLLRGTKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGHGQWTYQIYQELFKNLKTGKYARMKGT
HTNDVRQLVDVIQKVSTESIVLWGKTPKFKLPIQKETWEA

References
Author Title Citation
Margot, NA Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF. AIDS, 2002
Rhee, SY Distribution of human immunodeficiency virus type 1 protease and reverse transcriptase mutation patterns in 4,183 persons undergoing genotypic resistance testing. AAC, 2004