<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NRTI|NNRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, L74I, T215F K219W, N348I K101P, K103N   E6D, W88F, A98S, G196E, T200A, E203D, D218E, A288S, T296S, E297R, L301M, K311R, S322T, I329IV, Q334E, R356K, T386I, K390R, A400S P1H, N54I
>5288366431| codons 1-400
HISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPEIPYNTPV
FAIKKKNSTRWRKIVDFRELNKRTQDFFEVQLGIPHPSGLPKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIEQHRAKIDELRQHLLRWGFFTPEWKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVIPLSREAE
MELAENREILREPVHGVYYDPTKDLIAEVQKQGEGQWTYQIYQEPFKILKTGKYAKMRGA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWES

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    E35D, N37Q, R57K, L63P  
>5288366431| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMQLPGRWKPKMIGGIGGFIKVKQYD
QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Margot, NA Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF. AIDS, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005