<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NRTI|NNRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, L210LW, T215Y N348I K103N, Y181YC K238T K20R, K49R, V60VI, R83RK, A98S, I135L, E138EA, S162SGDN, R211K, E291D, E297EK, K311R, S322T, D324E, V365VI, K390R, E399G, A400S  
>4009367801| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNATPGIRYQYNVLPQGWKGSPAIFQGSMTKILEPFRKQNPDIVI
CQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDTWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDVIPLTKEAE
LELAENREILREPVHGVYYDPTKELIAEIQKQGQGQWTYQIYQEPFKILKTGKYARMRGA
HTNDIKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWGS

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    M36I, N37E, R57K, L63P, I64IV, E65D, K70R  
>4009367801| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEIELPGRWKPKMIGGIGGFIKVKQYD
QIPVDICGHRAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Margot, NA Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF. AIDS, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005