Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RC-007-045-296 | 045-29621 | South Africa | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTI | NA |
| 2 | ATV+D4T+DDI | 78 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I50L | G73S | K45R, L63P, A71V, V77I, I93L |
| >045-29621| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPRMIGGLGGFIKVRQYD QIPIEICGHKVISTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Colonno, RJ | Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens. | J Infect Dis, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |