<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MBA1294 MBA1294 Uganda 2007 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14KR, G16GE, L19P, K20I, M36I, R41K, L63A, E65D, L89M  
>MBA1294| codons 1-99
PQITLWQRPIVTVRIEGQPIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIAIDICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103KNRS   V35T, V60I, K82KR, K122E, D123S, I135T, S162A, D177E, I178M, T200TAIV, Q207E, R211K, V245EK, D250E, A272P, K277R, K281KR, L282C, T286A, V292VI, I293V, P294T, K311R, G335D, P345Q, F346Y, R356K, M357L, A360T, T377Q, K390R, A400T  
>MBA1294| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNRRTQDFWEVQLGIPHPAGLKKSKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPEMVI
YQYMDDLYVGSDLEIGQHRVKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCRCLRGAKALTEIVTLTEEAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEQYKNLKTGKYAKLRGT
HTNDVKQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWET

References
Author Title Citation
Lee, GQ Prevalence and Virologic Consequences of Transmitted HIV-1 Drug Resistance in Uganda. ARHR, 2014