<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MBA1437 MBA1437 Uganda 2007 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G16GE, K20I, E35DN, M36I, R41K, H69K, L89M  
>MBA1437| codons 1-99
PQITLWQRPLVTVKIEGQLIEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39KN, K122E, D123NT, K173S, Q174QR, D177E, V179I, I202V, Q207A, R211S, V245Q, A272P, T286A, E291S, V292I, I293V, P294T, E312D, V317VE, G335D, M357K, R358RK, G359S, A360AT, K366R, A371V, I375V, A376V, T377M, A400T  
>MBA1437| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DETFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSRNPEIII
YQYMDDLYVGSDLEIGQHRTKVEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTSIVTLTEEAE
LELAENREILKDPVHGEYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKKST
HTNDVRQLTEVVQKVVMESIVIWGKTPKFKLPIQKETWET

References
Author Title Citation
Lee, GQ Prevalence and Virologic Consequences of Transmitted HIV-1 Drug Resistance in Uganda. ARHR, 2014