<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MBA1075 MBA1075 Uganda 2007 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15IV, M36I, R41K, I62V, L63A  
>MBA1075| codons 1-99
PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QVAIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, V60I, S68G, K122E, D123S, T165I, D177E, I178V, Q197E, T200I, Q207E, R211K, V245K, D250E, A272P, K277R, L282C, T286A, V292I, I293V, D324E, G335D, T338S, P345Q, F346Y, R356K, A360T, E370A, T377L, S379C, K390R, A400T  
>MBA1075| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPEVVI
YQYMDDLYVGSDLEIGEHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCLRGAKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQDQWSYQIYQEQYKNLKTGKYAKMRGT
HTNDVKQLTAAVQKIALECIVIWGKTPKFRLPIQKETWET

References
Author Title Citation
Lee, GQ Prevalence and Virologic Consequences of Transmitted HIV-1 Drug Resistance in Uganda. ARHR, 2014