<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MBA1467 MBA1467 Uganda 2007 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K20V, M36I, R41K, C67Y, L89M  
>MBA1467| codons 1-99
PQITLWQRPIVTVKIGGQLVEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEIYGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KE       V35T, T39K, K43R, V60I, D121HY, K122E, P170PL, D177E, Q207A, R211S, V245K, D250E, A272P, K277R, L282C, T286A, I293V, S322A, D324DE, I329IV, K331KR, G335D, P345Q, F346Y, Y354H, R356K, M357MLST, A360T, A371V, A376S, T377H, S379C, K390R, A400T  
>MBA1467| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEREGKISKIGPENPYNTPI
FAIKKKDSTEWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILELFRKQNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCLRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPAKELIAEVQRQGQDQWTYQIYQEQYKNLKTGKHAKTRGT
HTNDVKQLTEVVQKISHECIVIWGKTPKFRLPIQKETWET

References
Author Title Citation
Lee, GQ Prevalence and Virologic Consequences of Transmitted HIV-1 Drug Resistance in Uganda. ARHR, 2014