<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV NA
2 3TC+D4T+EFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41N, I62V, L63H, H69K, I72IV, V82I, L89I, I93L  
>12ZAKS267| codons 40-99
GNWKPKMIGGIGGFIKVRQYDQVHIEICGKKAVGTVLVGPTPINIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N P225H K20R, V35T, E36A, T39E, K122E, D123S, I135L, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, L228Q, V245Q, A272P, K281R, E291D, V292VI, I293V, V317A, D324E, E328D, Q334N, G335D, T338TI, P345PT, F346Y, R356K, G359T, A371V, I375V, T377L, K390R, E404D  
>12ZAKS267| codons 1-433
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEHPFQWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKELIADIQKQGNDQWIYQIYQETYKNLKTGKYAKMRTA
HTNDVKQLTEVVQKVALESIVIWGKTPKFRLPIQKETWEAWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEP

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014