<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A L10F T12S, I15V, L19V, M36I, R41K, L63P, H69K, T74S, L89M, I93L  
>11ZAKS168| codons 1-99
PQITLWQRPFVSIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKLIGGIGGFVKVRQYD
QIPIEICGKKAIGSVLVGPTPANIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       E28K, K32E, V35T, E36A, S48T, K49KR, K122E, D123N, E169A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, I274V, E291D, V292I, I293V, P313T, V317A, F346Y  
>11ZAKS168| codons 1-346
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTAICTEMEKEGKITRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILAPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGVKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKETVHGAYYDPSKDLIAEIQKQGQGQWTYQIYQEPY

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014