<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, I54V, V82A   R41K, K55R, R57K, Q61H, L63T, H69K, A71V, I72K, T74S, L89M, I93L  
>11ZAKS171| codons 39-99
PGKWKPKIIGGVGGFVRVKQYDHITIEICGKKVKGSVLVGPTPANIIGRNMLTQLGCTLN
F

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V     V179E V35K, T39E, S48T, K122E, D123S, K173A, Q174R, D177E, T200E, Q207E, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V, K311R, V317A, I329V, Q334N, G335D E203KR
>11ZAKS171| codons 1-343
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIEI
YQYVDDLYVGSDLEIGQHREKIRELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILREPVHGAYYDPSKDLIAEVQKQGNDQWTYQIYQ

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014