<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M N88G L63P, A71IT, V77I  
>12ZAKS340| codons 39-99
PGRWKPKLIGGIGGFVKVRQYDQIPIEICGHKTIGTVLIGPTPANIIGRGLMTQIGCTLN
F

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, L210W, T215Y A62V, M184L, N348I L100I, K103N   P4PS, K20R, V35M, E44D, K102KR, T107S, L109I, I135T, S162C, V189I, Q197K, T200A, I202T, H208Y, R211K, H221Y, A272S, K277R, A288S, I293V, E297EK, E312EQ, S322A, Q334E, I341F, R356K, T386V, K390R  
>12ZAKS340| codons 1-437
PISSIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTELEKDGKISKIGPENPYNTPV
FVIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKRNKSVSVIDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI
YQYLDDLYIGSDLEIGKHRAKTEELRQYLWKWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGTKSLTEVVPLTKEAE
LELAENREILKQPVHGVYYDPAKDLIAEIQKQGEGQWTYQFYQEPFKILKTGKYAKMRGA
HTNDVKQLTEAVQKIATESIVIWGKVPKFRLPIQKETWEAWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGA

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014