<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+ABC+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A   R41K, R57K, L63P, H69K, T74S, L89M, I93L  
>12ZAKS204| codons 39-99
PGKWKPKMIGGIGGFVKVKQYDQIPIEICGKKAIGSVLVGPTPANIIGRNMLTQLGCTLN
F

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V K219E Y181C   E6K, V35T, E36A, T39E, S48T, V60I, K122E, S162C, K173A, D177E, T200A, Q207N, R211K, H221Y, V245Q, A272P, Q278H, K281R, E291D, V292I, S322T, Q334D, G335D  
>12ZAKS204| codons 1-345
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAQNPEIVI
CQYVDDLYVGSDLEIGQHRAKIEELRNHLLKWGFTTPDEKYQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCRLLRGTKALTDIIPLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGDDQWTYQIYQEP

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014