Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | K101KE, G190Q | K20R, V35T, E36A, T39E, S48T, K49KR, V60I, L109I, D121Y, K122E, E138Q, K173A, T200A, Q207E, V245Q, D250E, A272P, K275Q, K277R, Q278H, L283LI, T286A, E291D, V292I, I293V |
| >10ZAKS034| codons 1-307 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVIDVGDAYFSVPL YEDFRKYTAFTIPSINNQTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPDIVI YQYVDDLYVQSDLEIGQHRAKIEELREHLLRWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIQVRHLCKLIRGAKALTDIVPLTEEAE LELAENR |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| R41K, L63V, H69K, I93L |
| >10ZAKS034| codons 39-99 PGKWKPKMIGGIGGFIKVRQYDQIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLN F |
References
| Author | Title | Citation |
| Steegen, K | High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. | PLoS ONE, 2014 |