<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+TDF NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215F   Y188L V179E V8I, V35K, T39E, V60I, K102W, I135T, K173A, Q174K, D177E, T200A, Q207QE, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, M357K, R358K, G359S, E370D, T377M, K390R, K395R, E399D, A400T, E404D, E430R  
>12ZAKS295| codons 1-431
PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALKEICEEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKWKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIEI
YQYVDDLLVGSDLEIGQHRAKIEELREHLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKKSA
HTNDVKQLTDAVQKIAMESIVIWGKTPKFRLPIQRETWDTWWTDYWQATWIPEWEFVNTP
PLVKLWYQLRK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, I62V, L63V, H69K, T74S, L89M, I93L  
>12ZAKS295| codons 39-99
PGKWKPKMIGGIGGFIKVRQYDQVVIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014