<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115F, M184V   Y181C, G190A K101HQ V35T, E36A, T39E, S48T, K122E, D123N, S162C, K173T, D177E, T200A, E204K, Q207E, H221Y, L228Q, V245H, A272P, K275R, K277R, Q278C, T286A, E291D, V292I, I293V, E297K, P321PL, Q334E, G335D  
>12ZAKS220| codons 1-345
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAFFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTQNPEIVI
CQYVDDLYVASDLEIGQHRAKIEKLREHLLRWGFTTPDKKYQKEPPFQWMGYELHPDKWT
VQPIHLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVRCLCKLLRGAKALTDIVPLTKEAE
LELAENREILKEPVHGVYYDLSKDLIAEIQKQGEDQWTYQIYQEP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A   R41K, L63V, I66M, H69K, T74S, L89M, T91S, I93L  
>12ZAKS220| codons 39-99
PGKWKPKIIGGIGGFVKVRQYDQIVIEMCGKKAIGSVLVGPTPANIIGRNMLSQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014