<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69T_T, K70R, L74V, M184V D67G, K219Q L100I, K103N   I2V, P4T, V35T, T39E, K64N, I94L, V118I, K122E, D123S, I135T, T139K, S162D, E169K, K173A, Q174K, D177E, T200A, I202V, E203K, Q207E, R211K, F214L, D218E, L228H, V245Q, D250E, A272P, K277R, L283I, T286A, E291ED, V292VI, I293V  
>11ZAKS154| codons 1-333
PVSTIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV
FAINKKGSTRWRKVVDFRELNKRTQDFWEVQLGLPHPAGIKKNKSVTVLDVGDAYFSIPL
DESFRKYTAFTIPSTNNEKPGIRYQYNVLPQGWKGSPAIFQDSMTKILKPFRAKNPEIVI
YQYVDDLYVGSDLEIGQHRAKVKELREHLLKWGLTTPEQKHQKEPPFHWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, D60E, Q61E, L63P, H69K, I93L  
>11ZAKS154| codons 39-99
PGKWKPKMIGGIGGFIKVRQYEEIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014