<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+ABC+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, M184V K219N L100I, K103N   V35T, T39E, S48E, E53D, D123E, S162H, E169EA, K173A, V179VI, T200A, Q207N, R211RK, V245Q, A272P, K281R, E291D, V292VI, I293V, E312T, E328K  
>11ZAKS152| codons 1-328
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKIEKIGPDNPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILAPFRAQNPDIII
YQYVDDLYVGSDLEIGQHRAKIEELRNHLLKWGFTTPDNKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTDIVPLTEEAE
LELAENREILKTPVHGVYYDPSKDLIAK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, R57K, D60E, I62V, L63T, H69K, A71T, L89I, I93L  
>11ZAKS152| codons 39-99
PGKWKPKMIGGIGGFIKVKQYEQVTIEICGKKTIGTVLVGPTPVNIIGRNILTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014