<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L76V, V82A   R41K, Q61H, L63P, H69K, A71V, I93L  
>12ZAKS229| codons 39-99
PGKWKPKMIGGIGGFVKVRQYDHIPIEICGKKVIGTVVVGPTPANIIGRNLLTQLGCTLN
F

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       E28A, V35T, T39E, S48T, W88C, V118VI, K122E, D123GS, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, K277R, Q278QH, T286A, E291D, V292I, I293V, E297EK, D324E, Q334H  
>12ZAKS229| codons 1-345
PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPELVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGAKALTDIVPLTKEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGHGQWTYQIYQEP

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014