<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V       V35K, T39E, S48E, K101Q, I135IV, K173A, D177E, T200A, Q207R, R211K, V245Q, K277KR, E291D, V292I, I293V, I326V, Q334D, I341V, R356K, M357K, G359S, T377M, K390R, A400T, T403M, E404D  
>12ZAKS195| codons 1-423
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICEEMEKEGKIEKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRRHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGDGQWTYQVYQEPFKNLKTGKYAKKRSA
HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWETWWMDYWQATWIPEWEFVNTP
PLV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A   Q61QH, I62V, L63V, H69K, T74S, L89M, I93L  
>12ZAKS195| codons 39-99
PGRWKPKIIGGIGGFVKVRQYDHVVIEICGKKAIGSVVVGPTPANIIGRNMLTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014