<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101E, K103N, G190A   V35T, E36A, T39E, S48T, S105T, K122E, D123G, E138A, K173A, D177E, I178L, Q207E, R211K, F214L, V245Q, D250E, A272P, Q278Y, T286A, E291D, V292I, I293V, E297R, I329L, Q334N, G335D, R356K, G359T, V365I, T386I, K390R, T397M, A400T, E404D  
>12ZAKS346| codons 1-434
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKNKTVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPELVI
YQYVDDLYVASDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKYLCKLLRGAKALTDIVPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGNDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDIKQLTEAVQKIATESIVIWGKIPKFRLPIQKEMWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, H69K, L89M, I93L  
>12ZAKS346| codons 39-99
PGKWKPKMIGGIGGFIKVRQYDQILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014