<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   V106M, G190A F227L V35T, E36A, T39E, S48T, K122E, D123N, S162C, K173T, Q174R, D177E, T200A, Q207D, R211K, F214L, V245Q, E248D, D250E, A272P, K277R, A288S, E291D, V292I, I293V, D324E, Q334N, G335D, R356K, G359T, T369A, E370A, T377R, S379C, K390R, T397A, A400T, E404D, V435I  
>12ZAKS212| codons 1-440
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTRNPEIVI
YQYVDDLYVASDLEIGQHRAKIEELRDHLLKWGLTTPDKKHQKEPPLLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKSLTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGNDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLAAAVQKIARECIVIWGKTPKFRLPIQKEAWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETF

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, I62V, L63V, H69K, T74A, L89M, I93L  
>12ZAKS212| codons 39-99
PGKWKPKMIGGIGGFIKVRQYDQVVIEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014