<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I47A, V82A   R41K, R57K, L63P, H69Q, A71V, I93L  
>12ZAKS319| codons 39-99
PGKWKPKMAGGIGGFIKVKQYDQIPIEICGQKVIGTVLVGPTPANIIGRNLLTQLGCTLN
F

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V       I2V, V35T, T39E, S48T, K122E, I135L, E138A, I142T, S162C, G196E, T200A, Q207G, R211RK, P243T, V245Q, A272S, K277R, T286A, E291D, V292I, D324E, I329L, Q334N, G335D, R356K, G359T, T377R, S379C, K390R, E399D, A400T, E404D, V417I, E432D, V435A  
>12ZAKS319| codons 1-438
PVSPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSLNNATPGTRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIEQHRAKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQTIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDIIPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAELQKQGNDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIARECIVIWGKTPKFRLPIQKETWDTWWTDYWQATWIPEWEFINTP
PLVKLWYQLEKDPIAGAE

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014