Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 10ZAKS037 | 10ZAKS037 | South Africa | 2010 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+LPV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54V, L76V, V82A, I84V | R41RK, Q61QR, L63P, H69K, A71V, I93L |
| >10ZAKS037| codons 39-99 PGKWKPKIIGGIGGFVKVRQYDRIPIEICGKKVIGTVVVGPTPANVIGRNLLTQLGCTLN F |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V | E6EK, V35T, E36A, T39E, S48T, K122E, D123N, I135M, K173I, Q174K, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, E291D, V292I, I293V, E308Q |
| >10ZAKS037| codons 1-308 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENRQ |
References
| Author | Title | Citation |
| Steegen, K | High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. | PLoS ONE, 2014 |