<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V A62V V106M, Y188C   E6EK, V35T, E36A, T39E, S48ST, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, I257V, A272P, T286A, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, V372VI, T377Q, S379C, K388R, K390R, A400T, E404D S68SDGN, E291DN
>12ZAKS328| codons 1-434
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FVIKRKDNTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYVDDLCVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDVQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTNIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRRTA
HTNDVKQLTEAIQKIAQECIVIWGKTPRFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, D60E, Q61E, I62V, L63P, H69K, L89M, I93L  
>12ZAKS328| codons 39-99
PGKWKPKMIGGIGGFIKVRQYEEVPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014