<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A   Q61H, I62V, L63P, H69K, L89I, T91S, I93L  
>12ZAKS323| codons 39-99
PGRWKPKIIGGIGGFVKVRQYDHVPIEICGKKAIGTVVVGPTPANIIGRNILSQLGCTLN
F

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       V35T, E36A, T39D, S48T, K82KR, K122E, D123N, T139M, I142V, K173A, T200A, Q207K, R211T, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293IV, I326IV, G335D, R356K, M357R, R358RK, G359S, A360AT, T377L, K390R, A400T, E404D, V417I, K431T, E432D  
>12ZAKS323| codons 1-433
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNRRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNEMPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRKHLLTWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRKST
HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFINTP
PLVKLWYQLETDP

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014