<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, D67DN, M184MI   V106VM, Y181YC, G190A V179DE K20R, V35T, T39E, V60I, K122E, D123N, I135T, E138A, T165I, T200A, E204Q, Q207E, R211K, F214L, H221HY, V245Q, E248D, A272P, K277R, Q278H, T286A, E291D, V292I, I293V, D324E, I329L, K331R, Q332R  
>10ZAKS031| codons 1-332
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPI
FAIKRKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPDIEI
CQYIDDLYVASDLEIGQHRAKIEQLREHLLKWGLTTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRHLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAELQRR

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, D60E, L63A, H69K, V82I, L89M, I93L  
>10ZAKS031| codons 39-99
PGKWKPKMIGGIGGFIKVRQYEQIAIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014