<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
11ZAKS098 11ZAKS098 South Africa 2011 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ABC+EFV NA
2 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, L74LV, M184V V75VIM V106M F227L T7TA, M16MV, V35T, E36A, T39E, K64R, K102Q, A158S, S162C, K173A, Q174K, D177E, I178L, T200A, K201KR, E203K, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334D, G335D, N348H, R356K, G359CST, E370A, T386V, K390R, A400T, E404D, V435A  
>11ZAKS098| codons 1-440
PISPIEAVPVKLKPGVDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV
FAIRRKDSTKWRKVMDFRELNKRTQDFWEVQLGIPHPAGLKQKKSMTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQCSMTKILEPFRAKNPELVI
YQYVDDLYVGSDLEIGQHRARIKELREHLLKWGFTTPDKKHQKEPPLLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDDQWTYQIYQEPFKHLKTGKYAKMRTA
HTNDVKQLTAAVQKIATESIVIWGKVPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETF

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, Q61D, H69K, T74S, L89M, I93L  
>11ZAKS098| codons 39-99
PGKWKPKMIGGIGGFIKVRQYDDILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014