<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, Q151M, M184V A62V, V75I, F116Y V106M, G190A F227L V35T, T39E, S68G, T69I, K102E, K122E, K173T, D177E, I178L, V179I, T200A, I202V, Q207DE, R211RK, F214L, V245K, A272P, R284K, T286A, E291D, V292I, I293V, E297K, Q334D, G335D, R356K, M357R, G359T, V365I, K366R, T377M, K385KR, K390R, A400T, E404D, I434M, V435T  
>11ZAKS095| codons 1-438
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEKEGKISKIGPENPYNTPV
FVIKKKDGIKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKEKKSMTVLDVGDAYYSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRTQNPELII
YQYVDDLYVASDLEIGQHRAKVEELREHLLKWGLTTPDKKHQKEPPLLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGAKALTDIVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKRRTA
HTNDIRQLTEAVQKIAMESIVIWGRTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPMTGAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, H69K, I72IM, L89M, I93L  
>11ZAKS095| codons 39-99
PGKWKPKMIGGIGGFIKVRQYDQILIEICGKKAMGTVLVGPTPVNIIGRNMLTQLGCTLN
F

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014