<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+ABC+LPV NA
2 3TC+D4T+EFV NA
3 AZT+DDI+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82S   R41K, R57K, Q61H, I62V, L63V, H69K, A71V, T74S, L89M, I93L  
>12ZAKS260| codons 39-99
PGKWKPKIIGGIGGFVKVKQYDHVVIEICGKKVIGSVLVGPTPSNIIGRNMLTQLGCTLN
F

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, L74I, Y115F, M184V K219Q G190A   V35T, E36A, T39E, V60I, K122E, D123S, E138A, T139A, T165I, K173T, Q174K, V179I, T200A, E203K, Q207E, L210S, R211M, F214L, D218E, V245Q, A272P, V292I, I293V, E297K, S322G, Q334N, G335D  
>12ZAKS260| codons 1-345
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPI
FAIKKKNSDRWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFFSVPL
DESFRKYTAFTIPSINNAAPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRTKNPDIII
YQYVDDLYVASDLEIGQHRAKIKELREHLSMWGLTTPEQKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIVPLTKEAE
LELAENREILKEPVHGVYYDPGKDLIAEIQKQGNDQWTYQIYQEP

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014