<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+ABC+LPV NA
2 3TC+D4T+EFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, L63T, H69K, L89M, I93L  
>12ZAKS333| codons 39-99
PGKWKPKMIGGIGGFIKVRQYDQITIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLN
F

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y   K101E, G190S   E28K, V35T, T39E, E44D, V118I, K122E, D123DN, K173A, Q174K, D177E, T200A, E203D, Q207E, H208Y, R211K, H221Y, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, D324E, G335D, A355S, R356K, G359T, T369V, E370G, I375V, A376AG, T377L, S379C, K390R, A400M, E404D  
>12ZAKS333| codons 1-434
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIKALTEICEELEKDGKISKIGPENPYNTPV
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYVDDLYVSSDLEIGQHRAKIDELREYLWKWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYSKMRTA
HTNDVKQLVGAVQKVGLECIVIWGKTPKFRLPIQKETWEMWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPI

References
Author Title Citation
Steegen, K High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen. PLoS ONE, 2014