<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
17 17_275 Russia 2011 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 3TC+DDI+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54IV   E35D, M36I, R41K, L63I, H69K, V77I, L89M, I93L  
>17_275| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVRQYD
QIIIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  A62V   G190F V35I, E36D, T39E, D123N, A158S, K173S, Q174K, G196E, Q207A, L210LM, R211S, E248D  
>17_275| codons 1-251
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIDICEEMEKEGKISKIGPENPYNTPV
FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKNFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRSKNPDIVI
YQYMDDLYVFSDLEIEQHRTKIEELRAHLMSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPDKDS

References
Author Title Citation
Kolomeets, AN A uniquely prevalent nonnucleoside reverse transcriptase inhibitor resistance mutation in Russian subtype A HIV-1 viruses. AIDS, 2014